Topography induced stiffness alteration of stem cells influences osteogenic differentiation
Biomater. Sci., 2020, 8,2638-2652
DOI: 10.1039/D0BM00264J, Paper
DOI: 10.1039/D0BM00264J, Paper
Open Access
This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Liangliang Yang, Qi Gao, Lu Ge, Qihui Zhou, Eliza M. Warszawik, Reinier Bron, King Wai Chiu Lai, Patrick van Rijn
Topography-driven alterations to single cell stiffness rather than alterations in cell morphology, is the underlying driver for influencing cell biological processes, particularly stem cell differentiation.
The content of this RSS Feed (c) The Royal Society of Chemistry
Topography-driven alterations to single cell stiffness rather than alterations in cell morphology, is the underlying driver for influencing cell biological processes, particularly stem cell differentiation.
The content of this RSS Feed (c) The Royal Society of Chemistry
Highly responsive and rapid hydrogen peroxide-triggered degradation of polycaprolactone nanoparticles
Biomater. Sci., 2020, 8,2394-2397
DOI: 10.1039/C9BM02019E, Communication
DOI: 10.1039/C9BM02019E, Communication
Peng-Hao Hsu, Carina Arboleda, Alexandra Stubelius, Ling-Wei Li, Jason Olejniczak, Adah Almutairi
Nanoparticles formulated from fast-degrading oxidation-responsive polycaprolactone are responsive to 50 μM of H2O2.
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Nanoparticles formulated from fast-degrading oxidation-responsive polycaprolactone are responsive to 50 μM of H2O2.
The content of this RSS Feed (c) The Royal Society of Chemistry
The electrospinning of a thermo-responsive polymer with peptide conjugates for phenotype support and extracellular matrix production of therapeutically relevant mammalian cells
Biomater. Sci., 2020, 8,2611-2626
DOI: 10.1039/C9BM01965K, Paper
DOI: 10.1039/C9BM01965K, Paper
Open Access
This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
F. A. A. Ruiter, L. E. Sidney, K. L. Kiick, J. I. Segal, C. Alexander, F. R. A. J. Rose
The fabrication and application of a biocompatible peptide conjugated thermo-responsive fibrous scaffolds for cellular phenotype support and enzymatic-free passaging of mammalian cells.
The content of this RSS Feed (c) The Royal Society of Chemistry
The fabrication and application of a biocompatible peptide conjugated thermo-responsive fibrous scaffolds for cellular phenotype support and enzymatic-free passaging of mammalian cells.
The content of this RSS Feed (c) The Royal Society of Chemistry
A thermo-responsive, self-assembling biointerface for on demand release of surface-immobilised proteins
Biomater. Sci., 2020, 8,2673-2681
DOI: 10.1039/C9BM01957J, Paper
DOI: 10.1039/C9BM01957J, Paper
Angela Saccardo, Mikhail Soloviev, Enrico Ferrari
Engineering of the neuronal SNARE proteins yields chimeric bio-materials that reversibly assemble and disassemble at set temperatures.
The content of this RSS Feed (c) The Royal Society of Chemistry
Engineering of the neuronal SNARE proteins yields chimeric bio-materials that reversibly assemble and disassemble at set temperatures.
The content of this RSS Feed (c) The Royal Society of Chemistry
Nanomedicine – a promising therapy for hematological malignancies
Biomater. Sci., 2020, 8,2376-2393
DOI: 10.1039/D0BM00129E, Review Article
DOI: 10.1039/D0BM00129E, Review Article
Lifen Huang, Jun Huang, Junbin Huang, Hongman Xue, Zhiqing Liang, Jun Wu, Chun Chen
Nanoparticles (NPs) are used for the diagnosis and treatment of hematological tumors by loading various pharmacodynamic molecules.
The content of this RSS Feed (c) The Royal Society of Chemistry
Nanoparticles (NPs) are used for the diagnosis and treatment of hematological tumors by loading various pharmacodynamic molecules.
The content of this RSS Feed (c) The Royal Society of Chemistry
H2S-releasing amphiphilic dipeptide hydrogels are potent S. aureus biofilm disruptors
Biomater. Sci., 2020, 8,2564-2576
DOI: 10.1039/D0BM00241K, Paper
DOI: 10.1039/D0BM00241K, Paper
Yun Qian, Afnan Altamimi, Shaina Alston Yates, Santu Sarkar, Matthew Cochran, Mingjun Zhou, Nicole Levi-Polyachenko, John B. Matson
Hydrogen sulfide (H2S) is an endogenous signaling gas, and exogenous H2S administration has the potential for promoting wound healing. Here we investigate the antimicrobial effects of H2S-releasing hydrogels in the context of burn wound healing.
The content of this RSS Feed (c) The Royal Society of Chemistry
Hydrogen sulfide (H2S) is an endogenous signaling gas, and exogenous H2S administration has the potential for promoting wound healing. Here we investigate the antimicrobial effects of H2S-releasing hydrogels in the context of burn wound healing.
The content of this RSS Feed (c) The Royal Society of Chemistry
Spatial immobilization of endogenous growth factors to control vascularization in bone tissue engineering
Biomater. Sci., 2020, 8,2577-2589
DOI: 10.1039/D0BM00087F, Paper
DOI: 10.1039/D0BM00087F, Paper
Marta R. Casanova, Catarina Oliveira, Emanuel M. Fernandes, Rui L. Reis, Tiago H. Silva, Albino Martins, Nuno M. Neves
An engineered biofunctional system comprises endogenous BMP-2 and VEGF bound in a parallel pattern. It successfully enabled obtaining the spatial osteogenic and angiogenic differentiation of human hBM-MSCs under basal culture conditions.
The content of this RSS Feed (c) The Royal Society of Chemistry
An engineered biofunctional system comprises endogenous BMP-2 and VEGF bound in a parallel pattern. It successfully enabled obtaining the spatial osteogenic and angiogenic differentiation of human hBM-MSCs under basal culture conditions.
The content of this RSS Feed (c) The Royal Society of Chemistry
NIR-emitting semiconducting polymer nanoparticles for in vivo two-photon vascular imaging
Biomater. Sci., 2020, 8,2666-2672
DOI: 10.1039/C9BM02063B, Paper
DOI: 10.1039/C9BM02063B, Paper
Xiao-Ting Gong, Wenguang Xie, Jing-Jing Cao, Shengxiang Zhang, Kanyi Pu, Hao-Li Zhang
A NIR-emitting TPF probe (NESPN) was prepared using semiconducting polymers and used for continuously monitoring the whole process of ischemic stroke and subsequent reperfusion. This work provides a new and versatile tool for vascular research and diagnosis of vascular diseases.
The content of this RSS Feed (c) The Royal Society of Chemistry
A NIR-emitting TPF probe (NESPN) was prepared using semiconducting polymers and used for continuously monitoring the whole process of ischemic stroke and subsequent reperfusion. This work provides a new and versatile tool for vascular research and diagnosis of vascular diseases.
The content of this RSS Feed (c) The Royal Society of Chemistry
Injectable hydrogel systems with multiple biophysical and biochemical cues for bone regeneration
Biomater. Sci., 2020, 8,2537-2548
DOI: 10.1039/D0BM00104J, Paper
DOI: 10.1039/D0BM00104J, Paper
Weinan Cheng, Zhaozhao Ding, Xin Zheng, Qiang Lu, Xiangdong Kong, Xiaozhong Zhou, Guozhong Lu, David L. Kaplan
Tunable multiple angiogenic and osteogenic cues were introduced into hydrogel systems simultaneously to optimize the niches for bone regeneration.
The content of this RSS Feed (c) The Royal Society of Chemistry
Tunable multiple angiogenic and osteogenic cues were introduced into hydrogel systems simultaneously to optimize the niches for bone regeneration.
The content of this RSS Feed (c) The Royal Society of Chemistry
A medical adhesive used in a wet environment by blending tannic acid and silk fibroin
Biomater. Sci., 2020, 8,2694-2701
DOI: 10.1039/D0BM00322K, Paper
DOI: 10.1039/D0BM00322K, Paper
Xijie Gao, Qiyuan Dai, Longtao Yao, Hua Dong, Qingtao Li, Xiaodong Cao
A medical adhesive called TASK based on polyphenol-gel systems was developed and showed wet-adhesive, stretchable, self-healing and restorable properties.
The content of this RSS Feed (c) The Royal Society of Chemistry
A medical adhesive called TASK based on polyphenol-gel systems was developed and showed wet-adhesive, stretchable, self-healing and restorable properties.
The content of this RSS Feed (c) The Royal Society of Chemistry
Assembly of FN-silk with laminin-521 to integrate hPSCs into a three-dimensional culture for neural differentiation
Biomater. Sci., 2020, 8,2514-2525
DOI: 10.1039/C9BM01624D, Paper
DOI: 10.1039/C9BM01624D, Paper
Open Access
This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Carolina Åstrand, Veronique Chotteau, Anna Falk, My Hedhammar
The functionalized recombinant spider silk protein FN-silk can self-assemble into a 3D microfiber network. When combined with recombinant laminin521 it provides a 3D culture system suitable for expansion of hPSCs and following neural differentiation.
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The functionalized recombinant spider silk protein FN-silk can self-assemble into a 3D microfiber network. When combined with recombinant laminin521 it provides a 3D culture system suitable for expansion of hPSCs and following neural differentiation.
The content of this RSS Feed (c) The Royal Society of Chemistry
Bioinspired inorganic nanoparticles and vascular factor microenvironment directed neo-bone formation
Biomater. Sci., 2020, 8,2627-2637
DOI: 10.1039/D0BM00041H, Paper
DOI: 10.1039/D0BM00041H, Paper
Hwan D. Kim, Jungha Park, Sivashanmugam Amirthalingam, R. Jayakumar, Nathaniel S. Hwang
VEGF-overexpressing human tonsil-derived stem cells (VEGF-hTMSCs) and a whitlockite microenvironment induce vascularized bone tissue formation in biodegradable polymeric scaffolds.
The content of this RSS Feed (c) The Royal Society of Chemistry
VEGF-overexpressing human tonsil-derived stem cells (VEGF-hTMSCs) and a whitlockite microenvironment induce vascularized bone tissue formation in biodegradable polymeric scaffolds.
The content of this RSS Feed (c) The Royal Society of Chemistry
Enhanced selectivity, cellular uptake, and in vitro activity of an intrinsically fluorescent copper–tirapazamine nanocomplex for hypoxia targeted therapy in prostate cancer
Biomater. Sci., 2020, 8,2420-2433
DOI: 10.1039/C9BM01905G, Paper
DOI: 10.1039/C9BM01905G, Paper
Vera L. Silva, Abdessamad Kaassis, Ashkan Dehsorkhi, Cédrik-Roland Koffi, Maja Severic, Moustafa Abdelhamid, Duuamene Nyimanu, Christopher J. Morris, Wafa’ T. Al-Jamal
Cu(TPZ)2 complex as a promising hypoxia selective cytotoxin in prostate cancer.
The content of this RSS Feed (c) The Royal Society of Chemistry
Cu(TPZ)2 complex as a promising hypoxia selective cytotoxin in prostate cancer.
The content of this RSS Feed (c) The Royal Society of Chemistry
A nanosystem loaded with perfluorohexane and rose bengal coupled upconversion nanoparticles for multimodal imaging and synergetic chemo-photodynamic therapy of cancer
Biomater. Sci., 2020, 8,2488-2506
DOI: 10.1039/C9BM02081K, Paper
DOI: 10.1039/C9BM02081K, Paper
Hai-yan Wang, Li Hou, Hai-liang Li, Xu Wang, Yang Cao, Bo-yu Zhang, Jing-tao Wang, Shi-jie Wei, Hong-wan Dang, Hai-tao Ran
A novel nanosystem (FURH-PFH-NPs) combined with LIFU and laser irradiation realized multimodal imaging, targeted release of HCPT, UCNPs-RB and synergetic chemo-photodynamic therapy of cancer.
The content of this RSS Feed (c) The Royal Society of Chemistry
A novel nanosystem (FURH-PFH-NPs) combined with LIFU and laser irradiation realized multimodal imaging, targeted release of HCPT, UCNPs-RB and synergetic chemo-photodynamic therapy of cancer.
The content of this RSS Feed (c) The Royal Society of Chemistry
Super-assembled core/shell fibrous frameworks with dual growth factors for in situ cementum–ligament–bone complex regeneration
Biomater. Sci., 2020, 8,2459-2471
DOI: 10.1039/D0BM00102C, Paper
DOI: 10.1039/D0BM00102C, Paper
Tian Ding, Jianhua Li, Xingshuang Zhang, Lingqian Du, Yang Li, Dengwang Li, Biao Kong, Shaohua Ge
In this work, a super-assembled framework (SAF) was fabricated to achieve sequential delivery of bFGF and BMP-2 for in situ cementum–ligament–bone complex regeneration.
The content of this RSS Feed (c) The Royal Society of Chemistry
In this work, a super-assembled framework (SAF) was fabricated to achieve sequential delivery of bFGF and BMP-2 for in situ cementum–ligament–bone complex regeneration.
The content of this RSS Feed (c) The Royal Society of Chemistry
Dual-responsive click-crosslinked micelles designed for enhanced chemotherapy for solid tumors
Biomater. Sci., 2020, 8,2507-2513
DOI: 10.1039/D0BM00078G, Paper
DOI: 10.1039/D0BM00078G, Paper
Rong Jin, Jing Sun, Liefu Zhou, Xuelian Guo, Aoneng Cao
Core-crosslinked dual-responsive micelles can be readily constructed from a pair of clickable copolymers and applied for controlled release of anticancer drugs in cancer therapy.
The content of this RSS Feed (c) The Royal Society of Chemistry
Core-crosslinked dual-responsive micelles can be readily constructed from a pair of clickable copolymers and applied for controlled release of anticancer drugs in cancer therapy.
The content of this RSS Feed (c) The Royal Society of Chemistry
Biomimic strategies for modulating the interaction between particle adjuvants and antigen-presenting cells
Biomater. Sci., 2020, 8,2366-2375
DOI: 10.1039/C9BM02098E, Review Article
DOI: 10.1039/C9BM02098E, Review Article
Jie Wu, Guanghui Ma
The design strategies of particle adjuvants by mimicking natural pathogens to strengthen their interaction with antigen-presenting cells.
The content of this RSS Feed (c) The Royal Society of Chemistry
The design strategies of particle adjuvants by mimicking natural pathogens to strengthen their interaction with antigen-presenting cells.
The content of this RSS Feed (c) The Royal Society of Chemistry
Engineering red-emitting multi-functional nanocapsules for magnetic tumour targeting and imaging
Biomater. Sci., 2020, 8,2590-2599
DOI: 10.1039/D0BM00314J, Paper
DOI: 10.1039/D0BM00314J, Paper
Julie Tzu-Wen Wang, Umberto Martino, Rehan Khan, Maasoomeh Bazzar, Paul Southern, Dönüş Tuncel, Khuloud T. Al-Jamal
Self-red-emitting magnetic PLGA-PEG nanocapsules for optical imaging and magnetic tumour targeting.
The content of this RSS Feed (c) The Royal Society of Chemistry
Self-red-emitting magnetic PLGA-PEG nanocapsules for optical imaging and magnetic tumour targeting.
The content of this RSS Feed (c) The Royal Society of Chemistry
Trastuzumab targeted micellar delivery of docetaxel using dendron–polymer conjugates
Biomater. Sci., 2020, 8,2600-2610
DOI: 10.1039/C9BM01764J, Paper
DOI: 10.1039/C9BM01764J, Paper
Burcu Sumer Bolu, Bianka Golba, Amitav Sanyal, Rana Sanyal
Incorporation of a therapeutic antibody into nanosized drug delivery systems can improve their target specificity.
The content of this RSS Feed (c) The Royal Society of Chemistry
Incorporation of a therapeutic antibody into nanosized drug delivery systems can improve their target specificity.
The content of this RSS Feed (c) The Royal Society of Chemistry
Tumor localization of oncolytic adenovirus assisted by pH-degradable microgels with JQ1-mediated boosting replication and PD-L1 suppression for enhanced cancer therapy
Biomater. Sci., 2020, 8,2472-2480
DOI: 10.1039/D0BM00172D, Paper
DOI: 10.1039/D0BM00172D, Paper
Haishi Qiao, Xingmei Chen, Qiming Wang, Junmei Zhang, Dechun Huang, Enping Chen, Hongliang Qian, Yinan Zhong, Qi Tang, Wei Chen
Illustration of pH-degradable microgels (MGs) for the simultaneous encapsulation of OA and JQ1 for an enhanced oncolytic viral treatment with JQ1-meidated boosting viral replication and PD-L1 suppression.
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Illustration of pH-degradable microgels (MGs) for the simultaneous encapsulation of OA and JQ1 for an enhanced oncolytic viral treatment with JQ1-meidated boosting viral replication and PD-L1 suppression.
The content of this RSS Feed (c) The Royal Society of Chemistry
A riboflavin–ultraviolet light A-crosslinked decellularized heart valve for improved biomechanical properties, stability, and biocompatibility
Biomater. Sci., 2020, 8,2549-2563
DOI: 10.1039/C9BM01956A, Paper
DOI: 10.1039/C9BM01956A, Paper
Chungeng Liu, Weihua Qiao, Hong Cao, Jinchi Dai, Fei Li, Jiawei Shi, Nianguo Dong
Riboflavin–ultraviolet light A could effectively crosslink a decellularized heart valve to improve its biomechanical properties, stability and biocompatibility.
The content of this RSS Feed (c) The Royal Society of Chemistry
Riboflavin–ultraviolet light A could effectively crosslink a decellularized heart valve to improve its biomechanical properties, stability and biocompatibility.
The content of this RSS Feed (c) The Royal Society of Chemistry
In situ conversion of rose bengal microbubbles into nanoparticles for ultrasound imaging guided sonodynamic therapy with enhanced antitumor efficacy
Biomater. Sci., 2020, 8,2526-2536
DOI: 10.1039/C9BM02046B, Paper
DOI: 10.1039/C9BM02046B, Paper
Rui Hou, Xiaolong Liang, Xiaoda Li, Xu Zhang, Xiaotu Ma, Fan Wang
Sonosensitizer microbubbles enhance drug accumulation and the antitumor efficacy of sonodynamic therapy by ultrasound mediated micro to nano conversion.
The content of this RSS Feed (c) The Royal Society of Chemistry
Sonosensitizer microbubbles enhance drug accumulation and the antitumor efficacy of sonodynamic therapy by ultrasound mediated micro to nano conversion.
The content of this RSS Feed (c) The Royal Society of Chemistry
Naturally available hypericin undergoes electron transfer for type I photodynamic and photothermal synergistic therapy
Biomater. Sci., 2020, 8,2481-2487
DOI: 10.1039/D0BM00021C, Paper
DOI: 10.1039/D0BM00021C, Paper
Zhen Ke, Aize Xie, Jianjiao Chen, Zhenyuan Zou, Lei Shen, Yansong Dai, Dengfeng Zou
Hypericin undergoing electron transfer can be used for type I PDT and PTT.
The content of this RSS Feed (c) The Royal Society of Chemistry
Hypericin undergoing electron transfer can be used for type I PDT and PTT.
The content of this RSS Feed (c) The Royal Society of Chemistry
Oral biofilm elimination by combining iron-based nanozymes and hydrogen peroxide-producing bacteria
Biomater. Sci., 2020, 8,2447-2458
DOI: 10.1039/C9BM01889A, Paper
DOI: 10.1039/C9BM01889A, Paper
Yanqiu Wang, Xinyu Shen, Shang Ma, Qianqian Guo, Wei Zhang, Lu Cheng, Liming Ding, Zhuobin Xu, Jing Jiang, Lizeng Gao
Combining nanozymes and bacteria to eliminate dental biofilms in a mixed-species model.
The content of this RSS Feed (c) The Royal Society of Chemistry
Combining nanozymes and bacteria to eliminate dental biofilms in a mixed-species model.
The content of this RSS Feed (c) The Royal Society of Chemistry
Additively manufactured functionally graded biodegradable porous zinc
Biomater. Sci., 2020, 8,2404-2419
DOI: 10.1039/C9BM01904A, Paper
DOI: 10.1039/C9BM01904A, Paper
Open Access
This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.
Y. Li, P. Pavanram, J. Zhou, K. Lietaert, F. S. L. Bobbert, Yusuke Kubo, M. A. Leeflang, H. Jahr, A. A. Zadpoor
First report on the effect of topology design on the biodegradation, mechanical properties, and cell responses of additively manufactured Zn.
The content of this RSS Feed (c) The Royal Society of Chemistry
First report on the effect of topology design on the biodegradation, mechanical properties, and cell responses of additively manufactured Zn.
The content of this RSS Feed (c) The Royal Society of Chemistry
Multifunctional Antibacterial Dental Sealants Suppress Biofilms Derived from Children at High Risk of Caries
Biomater. Sci., 2020, Accepted Manuscript
DOI: 10.1039/D0BM00370K, Paper
DOI: 10.1039/D0BM00370K, Paper
Maria Salem Ibrahim, Isadora Martini Garcia, Taissa Vila, Abdulrahman A. Balhaddad, Fabricio Mezzomo Collares, Michael D Weir, Huakun Xu, Mary Anne Melo
Dental caries in children is a leading worldwide concern for oral health. Combining antibacterial and remineralizing additives within dental sealants is a promising approach for caries prevention. Saliva contains oral...
The content of this RSS Feed (c) The Royal Society of Chemistry
Dental caries in children is a leading worldwide concern for oral health. Combining antibacterial and remineralizing additives within dental sealants is a promising approach for caries prevention. Saliva contains oral...
The content of this RSS Feed (c) The Royal Society of Chemistry
A conductive PEDOT/alginate porous scaffold as a platform to modulate the biological behaviors of brown adipose-derived stem cells
Biomater. Sci., 2020, Advance Article
DOI: 10.1039/C9BM02012H, Paper
DOI: 10.1039/C9BM02012H, Paper
Boguang Yang, Fanglian Yao, Lei Ye, Tong Hao, Yabin Zhang, Lei Zhang, Dianyu Dong, Wancai Fang, Yan Wang, Xiaoyang Zhang, Changyong Wang, Junjie Li
The development of three-dimensional conductive scaffolds is vital to support the adhesion, proliferation and myocardial differentiation of stem cells in cardiac tissue engineering.
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The development of three-dimensional conductive scaffolds is vital to support the adhesion, proliferation and myocardial differentiation of stem cells in cardiac tissue engineering.
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A disulfide based low molecular weight gel for the selective sustained release of biomolecules
Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00508H, Paper
DOI: 10.1039/D0BM00508H, Paper
Nitin D. Bansode, Kotagudda Ranganath Sindhu, Chloe Morel, Murielle Rémy, Julien Verget, Claudine Boiziau, Philippe Barthélémy
Constructing biocompatible soft materials via supramolecular approaches remains an important challenge for in vivo applications.
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The content of this RSS Feed (c) The Royal Society of Chemistry
Constructing biocompatible soft materials via supramolecular approaches remains an important challenge for in vivo applications.
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The content of this RSS Feed (c) The Royal Society of Chemistry
Fluorescence Imaging-Guided Multifunctional Liposomes for Tumor-Specific Phototherapy for Laryngeal carcinoma
Biomater. Sci., 2020, Accepted Manuscript
DOI: 10.1039/D0BM00249F, Paper
DOI: 10.1039/D0BM00249F, Paper
Di Wu, zheng zhao, nan wang, xinrui zhang, honghong yan, xiaoqi chen, yunyun fan, weiwei liu, xuekui liu
Reliable diagnosed and efficient targeted therapy regime is important and may in turn lead to more effective laryngeal carcinoma treatments. Multifunctional nano-theranostic agents demonstrate great potential in tumor theranostic applications....
The content of this RSS Feed (c) The Royal Society of Chemistry
Reliable diagnosed and efficient targeted therapy regime is important and may in turn lead to more effective laryngeal carcinoma treatments. Multifunctional nano-theranostic agents demonstrate great potential in tumor theranostic applications....
The content of this RSS Feed (c) The Royal Society of Chemistry
Disulfiram-Gold-Nanorod Integrate for Effective Tumor Targeting and Photothermal-Chemical Synergistic Therapy
Biomater. Sci., 2020, Accepted Manuscript
DOI: 10.1039/D0BM00062K, Paper
DOI: 10.1039/D0BM00062K, Paper
Chaoli Xu, Ting Zhang, Guangming Lu, Kun Chen, Jun Tao, Yunlei Zhang, Zhaogang Teng, Bin Yang
Herein, we successfully constructed a combined therapeutic nanoplatform with high tumor targeting for cancer treatment by integrating gold nanorods with disulfiram (denoted Au-DSF). The Au-DSF integrates possess a uniform length...
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Herein, we successfully constructed a combined therapeutic nanoplatform with high tumor targeting for cancer treatment by integrating gold nanorods with disulfiram (denoted Au-DSF). The Au-DSF integrates possess a uniform length...
The content of this RSS Feed (c) The Royal Society of Chemistry
ZBTB20-mediated titanium particle-induced peri-implant osteolysis by promoting macrophage inflammatory responses
Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00147C, Paper
DOI: 10.1039/D0BM00147C, Paper
Open Access
This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.
Junxiong Qiu, Peng Peng, Min Xin, Zhenkang Wen, Zhong Chen, Sipeng Lin, Manyuan Kuang, Yuan Fu, Guibin Fang, Shixun Li, Changchuan Li, Jiaji Mao, Ling Qin, Yue Ding
Aseptic loosening (AL) caused by wear particles released from implant surfaces is one of the main causes for the failure of artificial joints, which is initiated by macrophage inflammatory responses.
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Aseptic loosening (AL) caused by wear particles released from implant surfaces is one of the main causes for the failure of artificial joints, which is initiated by macrophage inflammatory responses.
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A Fe3+-crosslinked pyrogallol-tethered gelatin adhesive hydrogel with antibacterial activity for wound healing
Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00188K, Paper
DOI: 10.1039/D0BM00188K, Paper
Ning Han, Ziyang Xu, Chunyan Cui, Yuan Li, Dongfei Zhang, Meng Xiao, Chuanchuan Fan, Tengling Wu, Jianhai Yang, Wenguang Liu
A tunicate-inspired gelatin-based hydrogel prepared by a simple mixing method, exhibits strong adhesion and antibacterial capacity, and facilitates wound healing.
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A tunicate-inspired gelatin-based hydrogel prepared by a simple mixing method, exhibits strong adhesion and antibacterial capacity, and facilitates wound healing.
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19 F magnetic resonance imaging enabled real-time, non-invasive and precise localization and quantification of the degradation rate of hydrogel scaffolds in vivo
Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00278J, Paper
DOI: 10.1039/D0BM00278J, Paper
Qinghua Li, Zujian Feng, Huijuan Song, Jianhua Zhang, Anjie Dong, Deling Kong, Weiwei Wang, Pingsheng Huang
19 F MRI is able to precisely monitor the localization and quantify the degradation rate of implantable/injectable hydrogels in real-time and noninvasive manner, with no interference of endogenous background signals and limitation of penetration depth.
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19 F MRI is able to precisely monitor the localization and quantify the degradation rate of implantable/injectable hydrogels in real-time and noninvasive manner, with no interference of endogenous background signals and limitation of penetration depth.
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Photothermal augment stromal disrupting effects for enhanced Abraxane synergy chemotherapy in pancreatic cancer PDX mode
Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00549E, Paper
DOI: 10.1039/D0BM00549E, Paper
Tianhong Teng, Ronggui Lin, Ziguo Lin, Kun Ke, Xianchao Lin, Maoen Pan, Da Zhang, Heguang Huang
Preparation of Abraxane@MoSe2 and its PTT effect augment stromal disrupting effects for enhanced Abraxane synergy chemotherapy in pancreatic cancer PDX mode.
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Preparation of Abraxane@MoSe2 and its PTT effect augment stromal disrupting effects for enhanced Abraxane synergy chemotherapy in pancreatic cancer PDX mode.
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Overview of the application of inorganic nanomaterials in cancer photothermal therapy
Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00222D, Review Article
DOI: 10.1039/D0BM00222D, Review Article
Natanael Fernandes, Carolina F. Rodrigues, André F. Moreira, Ilídio J. Correia
Cancer photothermal therapy (PTT) has captured the attention of researchers worldwide due to its localized and trigger-activated therapeutic effect.
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Cancer photothermal therapy (PTT) has captured the attention of researchers worldwide due to its localized and trigger-activated therapeutic effect.
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A pH-responsive dissociable mesoporous silica-based nanoplatform enabling efficient dual-drug co-delivery and rapid clearance for cancer therapy
Biomater. Sci., 2020, Accepted Manuscript
DOI: 10.1039/D0BM00204F, Paper
DOI: 10.1039/D0BM00204F, Paper
Yongju He, Linjie Shao, Ibrahim Usman, Yao Hu, Anqiang Pan, Shuquan Liang, Hui Xu
The dilemma between tumor accumulation and renal clearance has severely limited the efficacy of mesoporous silica-based drug nanocarrier in cancer therapy. Herein, a pH-responsive dissociable mesoporous silica-based nanoplatform with efficient...
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The dilemma between tumor accumulation and renal clearance has severely limited the efficacy of mesoporous silica-based drug nanocarrier in cancer therapy. Herein, a pH-responsive dissociable mesoporous silica-based nanoplatform with efficient...
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Self-assembled nucleo-tripeptide hydrogels provide local and sustained doxorubicin release
Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00134A, Paper
DOI: 10.1039/D0BM00134A, Paper
Kiheon Baek, Alexander David Noblett, Pengyu Ren, Laura J. Suggs
Doxorubicin is intercalated within the nanofibril structure of self-assembled nucleo-peptide hydrogels and injection leads to decrease in tumor volume and greater concentration of chemotherapeutic relative to soluble form.
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Doxorubicin is intercalated within the nanofibril structure of self-assembled nucleo-peptide hydrogels and injection leads to decrease in tumor volume and greater concentration of chemotherapeutic relative to soluble form.
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Sustainable release of vancomycin from micro-arc oxidised 3D-printed porous Ti6Al4V for treating methicillin-resistant Staphylococcus aureus bone infection and enhancing osteogenesis in a rabbit tibia osteomyelitis model
Biomater. Sci., 2020, Advance Article
DOI: 10.1039/C9BM01968E, Paper
DOI: 10.1039/C9BM01968E, Paper
Teng Zhang, Qingguang Wei, Hua Zhou, Wenhao Zhou, Daoyang Fan, Xinhong Lin, Zehao Jing, Hong Cai, Yan Cheng, Xiaoguang Liu, Weishi Li, Chunli Song, Yun Tian, Nanfang Xu, Yufeng Zheng, Zhongjun Liu
Sustainable release of vancomycin from micro-arc oxidised 3D-printed porous Ti6A14V for treating MRSA bone infection and enhancing osteogenesis.
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Sustainable release of vancomycin from micro-arc oxidised 3D-printed porous Ti6A14V for treating MRSA bone infection and enhancing osteogenesis.
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Core–shell particles for drug-delivery, bioimaging, sensing, and tissue engineering
Biomater. Sci., 2020, Advance Article
DOI: 10.1039/C9BM01872G, Review Article
DOI: 10.1039/C9BM01872G, Review Article
Ratchapol Jenjob, Treethip Phakkeeree, Daniel Crespy
Core–shell particles offer significant advantages in their use for bioimaging and biosensors.
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Core–shell particles offer significant advantages in their use for bioimaging and biosensors.
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Protein cages and virus-like particles: from fundamental insight to biomimetic therapeutics
Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00159G, Minireview
DOI: 10.1039/D0BM00159G, Minireview
Nicole F. Steinmetz, Sierin Lim, Frank Sainsbury
Protein cages found in nature have evolved for a variety of purposes and this review focuses on how they are being co-opted for use in immunotherapy and therapeutic delivery.
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Protein cages found in nature have evolved for a variety of purposes and this review focuses on how they are being co-opted for use in immunotherapy and therapeutic delivery.
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Long-term delivery of alendronate through an injectable tetra-PEG hydrogel to promote osteoporosis therapy
Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00376J, Paper
DOI: 10.1039/D0BM00376J, Paper
Dawei Li, Jin Zhou, Mingming Zhang, Yuanzheng Ma, Yanyu Yang, Xue Han, Xing Wang
An alendronate-loaded tetra-PEG hydrogel, as an injectable and effective drug carrier, regulates the optimized release of therapeutic cargoes to promote osteoporosis therapy and bone regeneration.
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An alendronate-loaded tetra-PEG hydrogel, as an injectable and effective drug carrier, regulates the optimized release of therapeutic cargoes to promote osteoporosis therapy and bone regeneration.
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A photothermal-hypoxia sequentially activatable phase-change nanoagent for mitochondria-targeting tumor synergistic therapy
Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00003E, Paper
DOI: 10.1039/D0BM00003E, Paper
Jia Qu, Dengke Teng, Guoqing Sui, Shihui Guan, Yang Wang, Qimeihui Wang, Yuanqiang Lin, Haitao Ran, Zhigang Wang, Hui Wang
The advantages of PCM@Lip/IT NPs include mitochondrial-targeting, on-demand drug release, and prodrug activation by hypoxia with guidance/monitoring by PA and FL imaging.
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The advantages of PCM@Lip/IT NPs include mitochondrial-targeting, on-demand drug release, and prodrug activation by hypoxia with guidance/monitoring by PA and FL imaging.
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A TRACER culture invasion assay to probe the impact of cancer associated fibroblasts on head and neck squamous cell carcinoma cell invasiveness
Biomater. Sci., 2020, Advance Article
DOI: 10.1039/C9BM02017A, Paper
DOI: 10.1039/C9BM02017A, Paper
Teresa Dean, Nancy T. Li, Jose L. Cadavid, Laurie Ailles, Alison P. McGuigan
A novel 3D in vitro co-culture platform to explore the interactions between cancer-associated fibroblasts and tumour cells that drive increased tumour cell invasion and the impact of matrix density.
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A novel 3D in vitro co-culture platform to explore the interactions between cancer-associated fibroblasts and tumour cells that drive increased tumour cell invasion and the impact of matrix density.
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Dendritic cells reprogrammed by CEA messenger RNA loaded multi-functional silica nanospheres for imaging-guided cancer immunotherapy
Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00395F, Communication
DOI: 10.1039/D0BM00395F, Communication
Yue Hu, Yuyin Tang, Xiao-Jing Zhang, Xiao-Tong Yang, Ying-Ying Tang, Su Li, Linyu Hu, Peng Chen, Dong Zhu
Multi-functional and hierarchically structured silica nanospheres are rationally designed and fabricated, which encapsulate quantum dots to permit near infrared deep tissue imaging and are loaded with carcinoembryonic antigen messenger RNA (CEAmRNA) to enable stable and abundant antigen expression in DCs.
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Multi-functional and hierarchically structured silica nanospheres are rationally designed and fabricated, which encapsulate quantum dots to permit near infrared deep tissue imaging and are loaded with carcinoembryonic antigen messenger RNA (CEAmRNA) to enable stable and abundant antigen expression in DCs.
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Messenger RNA/polymeric carrier nanoparticles for delivery of heme oxygenase-1 gene in the post-ischemic brain
Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00076K, Paper
DOI: 10.1039/D0BM00076K, Paper
Jungju Oh, Sang-Mi Kim, Eun-Hye Lee, Minkyung Kim, Youngki Lee, Seung Hwan Ko, Ji Hoon Jeong, Chang-Hwan Park, Minhyung Lee
Heme oxygenase-1 messenger RNA (HO1-mRNA) was delivered into the post-ischemic brain, using a polymeric carrier. Therapeutic efficacy of HO1-mRNA delivery was compared with that of HO1-plasmid DNA (HO1-pDNA) in ischemia-reperfusion rat models.
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Heme oxygenase-1 messenger RNA (HO1-mRNA) was delivered into the post-ischemic brain, using a polymeric carrier. Therapeutic efficacy of HO1-mRNA delivery was compared with that of HO1-plasmid DNA (HO1-pDNA) in ischemia-reperfusion rat models.
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Near-infrared-persistent luminescence/bioluminescence imaging tracking of transplanted mesenchymal stem cells in pulmonary fibrosis
Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00063A, Paper
DOI: 10.1039/D0BM00063A, Paper
Yuyang Xia, Hongying Bao, Jie Huang, Xiaodi Li, Chenggong Yu, Zhijun Zhang, Haishui Wang
A dual-labeling strategy integrating near-infrared-persistent luminescence and RfLuc-based bioluminescence imaging techniques has been developed to track the transplanted stem cells, deepening the understanding of the role played by stem cells in PF treatment.
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A dual-labeling strategy integrating near-infrared-persistent luminescence and RfLuc-based bioluminescence imaging techniques has been developed to track the transplanted stem cells, deepening the understanding of the role played by stem cells in PF treatment.
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Enhanced nanoparticle accumulation by tumor-acidity-activatable release of sildenafil to induce vasodilation
Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00466A, Paper
DOI: 10.1039/D0BM00466A, Paper
Peng Zhang, Yu Zhang, Xiaoya Ding, Chunsheng Xiao, Xuesi Chen
An efficient strategy to selectively promote nanoparticle accumulation in solid tumors was developed by encapsulating sildenafil in cisplatin-incorporated polymeric micelles.
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An efficient strategy to selectively promote nanoparticle accumulation in solid tumors was developed by encapsulating sildenafil in cisplatin-incorporated polymeric micelles.
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Antibiofilm coatings based on protein-engineered polymers and antimicrobial peptides for preventing implant-associated infections
Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00155D, Paper
DOI: 10.1039/D0BM00155D, Paper
Sergio Acosta, Arturo Ibañez-Fonseca, Conrado Aparicio, J. Carlos Rodríguez-Cabello
Protein-engineered polymers can be used as multivalent platforms for AMP tethering on implant surfaces as cytocompatible coatings with strong antibiofilm properties.
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Protein-engineered polymers can be used as multivalent platforms for AMP tethering on implant surfaces as cytocompatible coatings with strong antibiofilm properties.
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An engineered exosome for delivering sgRNA:Cas9 ribonucleoprotein complex and genome editing in recipient cells
Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00427H, Paper
DOI: 10.1039/D0BM00427H, Paper
Yangyang Ye, Xiang Zhang, Fei Xie, Bin Xu, Ping Xie, Ting Yang, Qian Shi, Chen-Yu Zhang, Yujing Zhang, Jiangning Chen, Xiaohong Jiang, Jing Li
CRISPR-Cas9 components delivered by engineered exosomes achieve genome editing in recipient cells.
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CRISPR-Cas9 components delivered by engineered exosomes achieve genome editing in recipient cells.
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The potential role of borophene as a radiosensitizer in boron neutron capture therapy (BNCT) and particle therapy (PT)
Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00318B, Communication
DOI: 10.1039/D0BM00318B, Communication
Pengyuan Qi, Qianyuan Chen, Dong Tu, Songhuan Yao, Yupeng Zhang, Jike Wang, Conghua Xie, Chunxu Pan, Hao Peng
The potential role of borophene as a radiosensitizer in PT and BNCT was investigated.
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The potential role of borophene as a radiosensitizer in PT and BNCT was investigated.
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